Office of
Research

College of Human Medicine




Office of
Research

Total Value Name of Award / Description of Study Project Start Project End Awarded by Principal Investigator Unit
$1,521,143 DNA Structure Directed AID Deamination During Immunoglobulin Isotype Switching 7/24/18 6/30/22 NIH Kefei Yu, PhD
Associate Professor
Microbiology and Molecular Genetics
$461,318 Novel ODC Inhibitor Phaseolotoxin n Neuroblastoma 8/21/18 7/31/20 National Cancer Institute Andre Bachmann, PhD, Professor, Associate Chair for Research, David Monsma, Industrial Hygienist, Thomas Dexheimer, PhD, Manager of Assay Development and Drug Repurposing, Edmund Ellsworth, PhD, Professor Pediatrics and Human Development
$451,111 Targeting Glucose Metabolism for the Treatment of Hepatocellular Carcinoma 4/1/18 7/31/19 NIH Bin Chen, PhD, Assistant Professor Pediatrics and Human Development
$426,250 Mechanistic understanding of HIV-1 broad neutralizing antibody evolution 2/7/18 1/31/20 NIH Kefei Yu, PhD
Associate Professor
Microbiology and Molecular Genetics
$420,546 A novel mouse model to study DNA ligase 3 function in vivo 5/21/18 4/30/20 NIH Kefei Yu, PhD
Associate Professor
Microbiology and Molecular Genetics
$98,050 Improving Pharmacokinetics and Efficacy of DFMO in Neuroblastoma 7/1/18 6/30/19 St. Baldrick's Foundation Andre' Bachmann, PhD, Professor, Associate Chair for Research Pediatrics and Human Development
$85,000 URMC-099 in in vivo AAV-hSYN and in vitro Dopaminergic Neuron Models 9/1/18 12/31/19 Michael J. Fox Foundation Fredric P. Manfredsson, Ph.D., Assistant Professor Translational Science and Molecular Medicine
$7,531 Safety and Efficacy of Turoctocog Alfa Pegol (N8-GP) in Prophylaxis and Treatment of Bleeds in Previously N8-GP Treated Patients with Severe Haemophilia 4/1/18 3/31/21 Novo Nordisk Roshi Kulkarni, MD, Professor
Ajovi Scott-Emuakpor, MD, Professor
Jatin Rana, MD, Assistant Professor
Renuka Gera, MD, Professor, Assistant Dean
Aghiad Chamdin, MD, Assistant Professor
Pediatrics and Human Development
$3,500 A Global Epidemiologic Study to Determine the Prevalence of Neutralizing Antibodies and Related Adaptive Immune Responses to Adeno-Associated Virus (AAV) in Adults with Hemophilia 1/26/18 12/31/22 Baxalta US Inc Roshni Kulkarni, MD, Professor
Ajovi Scott-Emuakpor, MD, Professor
Jatin Rana, MD, Assistant Professor
Renuka Gera, MD, Professor, Assistant Dean
Aghiad Chamdin, MD, Assistant Professor
Pediatrics and Human Development
$5,765 Evaluation of Safety  Following Immune Tolerance Induction Treatment with Turoctocog Alfa in Patients with Hemophilia A Following Inhibitor Development in NN7170-4213 Trial 12/14/17 11/30/21 Novo Nordisk Roshni Kulkarni, MD, Professor Pediatrics and Human Development
$208,333 Evaluation of Silicosis, Asthma and COPD among Sand and Gravel and Stone Surface Miners”

Injury and Disease Exposure and Risk Factors - Examination of the Relationships between Mine Environment Exposures and the Development or Exacerbation of Asthma and COPD
1-Jul-18 31-Dec-19 Alpha Foundation Kenneth Rosenman
Professor of Medicine
Chief, Division of Occupational and Environmental Medicine
MSU Distinguished Professor Award (2010)
Medicine
$135,076 Environmental Microbial and Mammalian Biomolecular Responses to AhR Ligands - Administrative Supplement 7/13/18 3/31/19 NIEHS/NIH Brad Upham, PhD, Associate Professor Pediatrics and Human Development
$296,137 New Survival Analysis Methods for Longitudinal Studies of Childhood Dental Caries 7/1/18 6/30/20 NIH Chenxi Li, PhD, Assistant Professor Epidemiology and Biostatistics
$1,325,365 Methods and Software for High-dimensional Risk Prediction Research 7/1/18 5/31/22 NIH/Library of Medicine Qing Lu, PhD, Associate Professor Epidemiology and Biostatistics
$151,399 Impact Award - Prodromal Symptoms in the Sister Study 6/1/18 5/31/19 Parkinson's Disease Fd. Honglei Chen, MD, PhD, Professor Epidemiology and Biostatistics
$500,000 Food as Medicine for Older Adults with Chronic Health Conditions 7/1/18 6/30/20 MI Health Endowment Fund Jean Kerver, PhD, MSc, RD, Assistant Professor Epidemiology and Biostatistics
$3,000 Norman Kagan Endowed Scholarship in Graduate and Professional Studies, project title: Building Skills for End-of-Life Discussions in the Intensive Care Environment. bioethics.msu.edu/homepage/research 1-Jul-18 30-Apr-19 MSU Devan Stahl, PhD, Assistant Professor, Center for Ethics and Humanities in the Life Sciences and Department of Pediatrics and Human Development. Center for Ethics and Humanities in the Life Sciences
Total ValueName of Award / Description of StudyProject StartProject EndAwarded byPrincipal InvestigatorUnit
$300,000 Genetic Link Between Aging and Parkinson’s Disease 2018 2021 Gibby & Friends vs Parky Timothy J. Collier, Ph.D., Professor Translational Science and Molecular Science
$296,137 New Survival Analysis Methods for Longitudinal Studies of Childhood Dental Caries 07/01/2018 06/30/2020 NIH, RO3 Chenxi Li, PhD, Assistant Professor Epidemiology and Biostatistics
$300,000 BDNF Precision medicine for Parkinson’s disease 2018 2021 Gibby & Friends vs Parky Caryl E. Sortwell, Ph.D. Professor and Associate Translational Science and Molecular Science
$200,000 LRRK2 and Tau in Parkinson’s Disease 2018 2020 Gibby & Friends vs Parky Nicholas M. Kanaan, Ph.D., Associate Professor Translational Science and Molecular Science
$20,000 2018 Pearl J. Aldrich Award 07/01/2018 06/30/2019 Pearl J. Aldrich Endowment Caryl E. Sortwell, Ph.D. Professor and Associate Translational Science and Molecular Science
Total ValueName of Award / Description of StudyProject StartProject EndAwarded byPIUnit
$15,000 The Role of Priostin in Uterine Fibroid Pathogenesis 07/01/2018 06/30/2019 Society for Reproductive Investigation Amanda Patterson, PhD OB/GYN & Reproductive Biology
$31,375 Rho Kinase Inhibition via Brain-Penetrant Kadmon Compound for Neuroprotection in Parkinson's Disease 02/01/2018 01/31/2019 Michael J Fox Foundation Jeffrey MacKeigan, PhD OB/GYN & Reproductive Biology and
Translational Science and Molecular Medicine
$1,540,162 Implementing to sustain: Determining the minimum necessary intervention to maintain a postpartum depression prevention program (ROSE) in clinics providing prenatal services to low-income women 01/01/2018 12/31/2022 National Institute of Mental Health Jennifer Johnson, PhD Division of Public Health
$50,000 Mitochondrial disfunction in ARID1A mutant ovarian clear cell cancer. 07/01/2018 06/30/2019 MI Ovarian Cancer Alliance John Risinger, PhD OB/GYN & Reproductive Biology
$50,000 Study of the Molecular Mechanisms Involved in High Grade Serous Progression from Metaplasia 06/01/2018 05/31/2019 MI Ovarian Cancer Alliance Jose Teixeira, PhD OB/GYN & Reproductive Biology
$25,000 RAIND Seed Grant 07/01/2018 12/31/2019 MSU Karen Racicot, PhD OB/GYN & Reproductive Biology
$163,500 Defining the role of endometrium in endometriosis-associated ovarian cancer 01/01/2018 12/31/2020 American Cancer Society Michael Wilson, PhD OB/GYN & Reproductive Biology
$15,000 Therapeutic Targeting of Endometriotic Lesions by NOTCH Inhibition 07/01/2018 06/30/2019 Society for Reproductive Investigation Niraj Joshi, PhD OB/GYN & Reproductive Biology
$2,956,535 Women's Outcomes Research and Knowledge (WORK) 04/01/2018 03/31/2021 AbbVie Stacey Missmer, ScD OB/GYN & Reproductive Biology
$31,000 Translational Research in Pelvic Pain (TRiPP) 01/01/2018 03/31/2021 Oxford University Stacey Missmer, ScD OB/GYN & Reproductive Biology
Total ValueName of Award / Description of StudyProject StartProject EndAwarded byPrincipal InvestigatorUnit
$168,290 Rho Kinase Inhabitation via Brain-Penetrant Kadmon Compound for Neuroprotection in Parkinson’s Disease 04/13/2018 04/13/2019 The Michael J. Fox Foundation Caryl E. Sortwell, Ph.D. Professor and Associate Chair and Jeff MacKeigan, Ph.D., Professor Translational Science & Molecular Medicine and Obstetrics Gynecology & Reproductive Biology
$100,000 Modulation of Alpha-synuclein Expression via Beta 2-Adrenoreceptor Agonist Clenbuterol in the Preformed Fibril Synucleinopathy Model 06/01/2018 06/01/2019 The Michael J. Fox Foundation PI - Joseph R. Patterson, Ph.D., Postdoctoral Fellow Co-PI - Caryl E. Sortwell, Ph.D., Professor and Associate Chair Translational Science and Molecular Science
$309,094 Parkinson's Research Program Early Investigator Research Award for "Harnessing Neuropasticity Genes to Combat Synucleinopathy-Mediated Axonopathy" TBA TBA Parkinson's Research Program Joseph Patterson, Ph.D., Postdoctoral Fellow Translational Science and Molecular Science
$250,000 Evaluation of Silicosis, Asthma and COPD among Sand and Gravel and Stone Surface Miners. TBA TBA Alpha Foundation for the Improvement of Mine Safety and Health, Inc. Kenneth Rosenman, M.D. Division of Occupational & Environmental Medicine
$75,000 Worksite Intervention to Mitigate Child Take-Home Lead Exposure This 1-year proposal will implement a program of take-home lead exposure. TBA TBA Michigan Department of Health and Human Services PI: Kenneth Rosenman, M.D. Professor of Medicine Chief, Division of Occupational and Environmental Medicine Co-PI: Anthony Oliveri, PhD, MPH Assistant Professor Division of Occupational & Environmental Medicine Division of Occupational & Environmental Medicine